Pediatrics 2022

Ximena Gallegos Riofrio

Equinoccial technological University, Ecuador

Title: Hydroa Vacciniforme-Like Cutaneous T-Cell Lymphoma

Abstract

Hydroa vacciniforme (HV)-like cutaneous T-cell lymphoma (HVLL) is a controversial skin pathology because some cases appear as hydroa vacciniforme, whereas others progress to cutaneous T-cell lymphoma with or without angiocentricity. It is usually associated with infections of Epstein Barr viruses and NK-cell lymphomas and typically affects the pediatric population. Symptoms include facial edema, papules, vesicles, and blisters in the facial region, arms, legs, and areas exposed to sunlight that leave varioliform scars. There may be infiltration of the lips, eyelids, and nose, usually accompanied by comorbid infections and hypersensitivity to insect bites. Frequency is rare, but HVLL more commonly affects patients from South America and Asia. Its clinical management can be difficult and accompanied by a high index of malignancy, thus early diagnosis is essential for effective and timely management. The differential diagnosis is wide since it must be differentiated from types of T and NKcell lymphoma such as nasal lymphoma, in addition it may look like tropical diseases such as leishmanisis, or paracoccidioidomycosis, and. other entities.  When presenting in exposed areas often mimics systemic lupus erythematosus or even some kinds of porphyria. Some forms may respond better to therapy, but other patients especially with late diagnostics develop a systemic type of lymphoma with notable aggressiveness and low response to therapy. Due to the different responses of each patient and taking into account that some patients do not progress to malignant  systemic disease, it has been highly discussed whether this  disease should  be included into lymphomas classification and diagnosis. However,  the WHO lymphoid neoplasms classification with its last review (2016) places it within the lymphoproliferative disorders, Multiple modifications have been made in this classification, but we consider that this is a pathology with potential for a fatal outcome therefore, its existence must be taken into account to obtain a appropiated diagnosis and treatment.

Biography

Ximena Gallegos Riofrio is a Dermatological Physician graduated at the Central University of Ecuador, Teacher of the Dermatology Area of the Faculty of Health Sciences Eugenio Espejo of the Equinoccial Tecnological University of Quito Ecuador, Training in Dermatoscopy in the Hospital Clinics of Barcelona Spain, also several titles obtained  in the study of Dermatoscopy for the early diagnosis of skin cancer, Madrid Spain and Argentina. Associated Doctor with the Metropolitan Hospital of Quito Ecuador, several publications in dermatological magazines and participation in several World Dermatology Congresses, active member of the Iberolatinoamerican College of Dermatology (CI.LAD).