
Syamsidah Lubis
Prof. Dr. Chairuddin P. Lubis Hospital, IndonesiaPresentation Title:
The relationship of the degree of respiratory distress with serum zinc levels at 28-34 weeks of pregnancy at the neonatology unit of Prof Chairuddin Panusunan Lubis Hospital
Abstract
Background: Zinc plays a crucial role as an antioxidant in reducing oxidative damage, making it important for the protection and management of several respiratory diseases in neonates. Premature neonates are born while their lungs are still maturing, which can lead to inadequate antioxidant defenses and an increased susceptibility to lung injury. The incidence increases in gestational ages below 34 weeks.
Aim: This study approach to determine relationship of the degree of respiratory distress with serum zinc levels .
Methods: This observational analytic study with a cross-sectional design was carried out in RSUP Haji Adam Malik Medan and RS Prof. dr. Chairuddin P. Lubis from June to October 2024. There were 10 subjects who met the inclusion criteria. Blood samples are obtained through the umbilical cord ,then serum zinc levels are checked using the Inductively Coupled Plasma Mass method.spectrometry (ICP-MS), which can measure metal elements through blood. The degree of respiratory distress was assessed using the downe score after neonatal resuscitation. Categorical data are presented in frequencies and percentages. Correlation between Zink level with severity Respiratory Distress was assessed with Pearson correlation.
Results: The study included 10 subjects with varying degrees of respiratory distress: 3 cases (30%) had mild respiratory distress, 2 cases (20%) had moderate respiratory distress, and 5 cases (50%) had severe respiratory distress. Correlation Zink serum with respiratory was significant r count 0.456, indicating a correlation between serum zinc levels and respiratory distress. Significant differences were observed in serum zinc levels among the three groups (p < 0.05).
Conclusion: Neonates with respiratory distress are accompanied by decreased serum zinc levels.
Keywords: Respiratory distress, neonate, zinc
Biography
Syamsidah Lubis has completed her Medical doctor at the age 24 years and Pediatric Specialist at the age 29 years from University of North Sumatra. She is the head of perinatology unit of Prof. dr. Chairuddin P. Lubis Hospital, Indonesia. She is one of the staff of Pediatrics, Neonatology Division, University of North Sumatra/ Prof. dr. Chairuddin P. Lubis Hospital and also Head of Ponek. She has over 3 publications that have been published.